Potassium Deficit Equation:
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The potassium deficit calculation estimates how much potassium needs to be administered to correct hypokalemia (low potassium levels) based on the difference between current and desired serum potassium levels and the patient's weight.
The calculator uses the potassium deficit equation:
Where:
Explanation: The equation estimates the total body potassium deficit based on the difference between current and desired levels, adjusted for the patient's size.
Details: Accurate potassium deficit calculation is crucial for safe and effective correction of hypokalemia, preventing both under- and over-correction which can have serious cardiac consequences.
Tips: Enter current and desired potassium levels in mEq/L, weight in kg. All values must be positive numbers. Typical desired potassium level is 4.0 mEq/L.
Q1: Why is the distribution factor 0.4?
A: The 0.4 factor accounts for potassium's distribution between intracellular and extracellular spaces, as only about 40% of administered potassium remains in the extracellular compartment.
Q2: How quickly should potassium be replaced?
A: The rate depends on severity and symptoms. Generally, no more than 20 mEq/hr through peripheral IV, or 40 mEq/hr through central line with cardiac monitoring.
Q3: What are normal potassium levels?
A: Normal serum potassium is typically 3.5-5.0 mEq/L. Levels below 3.5 indicate hypokalemia, and below 2.5 is severe hypokalemia.
Q4: Are there limitations to this calculation?
A: This is an estimate. Actual requirements may vary based on acid-base status, renal function, and ongoing losses. Always monitor serum levels during replacement.
Q5: What about oral potassium replacement?
A: Oral replacement is preferred when possible and safer. The same calculation can guide total dose, divided into multiple oral doses.